John Pawlowski, MD, PhD is an assistant professor of anesthesiology at the Harvard Medical School (HMS). His interest in medical simulation started many years ago, as he sought ways to replace the use of dogs in medical education. With the development of high-fidelity, whole body mannequins, important physiology lessons could be taught in place of live animals. He has advanced the use of simulation in the instruction of basic science and patient safety in medicine. At HMS, Pawlowski designed the first simulation-based replacement to the dog lab. As Co- Director of the HMS pharmacology course, he pioneered the use of simulation to demonstrate pharmacological principles. As Co-Director of the Simulation and Skills Center at the Beth Israel Deaconess Medical Center, Dr. Pawlowski has extended the use of simulation-based educational tools for the training of healthcare providers. He was awarded the Nanci Alexander Activist Award in 2019. He is continuously reminded of the importance of animal-free methods of teaching by his dear sheepdog Cazzie.